CPT® Code 91300

Deleted

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, spike protein, preservative free, 30 mcg/0.3 mL dosage, diluent reconstituted, for intramuscular use

The CPT® Code 91300 refers to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, specifically designed to combat coronavirus disease (COVID-19). This vaccine utilizes a messenger RNA (mRNA) technology encapsulated in lipid nanoparticles (LNP), which is a method that allows the mRNA to be delivered effectively into human cells. The vaccine contains a dosage of 30 mcg in a 0.3 mL volume and is preservative-free, ensuring that it is safe for intramuscular administration. The mRNA included in the vaccine encodes the spike protein of the SARS-CoV-2 virus, which is critical for the virus's ability to infect human cells. Upon administration, the body's cells utilize the mRNA as a template to produce the spike protein, which is then recognized by the immune system as a foreign entity. This recognition triggers an immune response, leading to the production of antibodies that can neutralize the virus if the individual is exposed in the future. The vaccine is prepared by reconstituting the mRNA-LNP with a diluent, specifically preservative-free normal saline, prior to administration. It is important to note that while this code reports the supply of the vaccine itself, the actual injection of the vaccine is reported separately using the appropriate administration code, which varies based on the dose given. This vaccine is part of a two-dose series, with a booster dose now available for populations recommended by the Centers for Disease Control and Prevention (CDC).