© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 91306 refers to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, specifically designed to combat coronavirus disease (COVID-19). This vaccine utilizes a novel approach by employing messenger RNA (mRNA) encapsulated in lipid nanoparticles (LNP), which is a cutting-edge technology in vaccine development. The mRNA contained in this vaccine encodes the spike protein of the SARS-CoV-2 virus, which is critical for the virus's ability to infect human cells. Upon administration, the mRNA instructs the body's cells to produce copies of the spike protein, which the immune system identifies as foreign. This triggers an immune response, leading to the production of antibodies that can recognize and neutralize the virus if the individual is exposed in the future. The vaccine is preservative-free and is administered in a dosage of 50 mcg per 0.25 mL via intramuscular injection. It is important to note that this code specifically reports the supply of Moderna's lower-dose vaccine product, which is intended for use as a booster for individuals aged 18 and older who have already received the initial Moderna vaccine. The administration of the vaccine itself is reported separately using the appropriate administration code, ensuring accurate billing and documentation for healthcare providers.
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