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Official Description

Professional services for allergen immunotherapy in the office or institution of the prescribing physician or other qualified health care professional, including provision of allergenic extract; 3 stinging insect venoms

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Allergen immunotherapy, as described by CPT® Code 95132, is a specialized treatment aimed at managing allergies specifically related to stinging insects, which include bees, wasps, hornets, and yellow jackets. This therapeutic approach is designed to desensitize individuals to these allergens, thereby reducing the severity of allergic reactions upon exposure. The process begins with allergy testing, which is conducted separately to identify the specific stinging insect allergen(s) that trigger the patient's allergic responses. Once the allergens are identified, a tailored immunotherapy schedule is established, consisting of two distinct phases: the build-up phase and the maintenance phase. During the build-up phase, patients receive progressively increasing doses of the allergenic extract(s) through injections, typically administered in the upper arm, with frequency ranging from one to three times per week. This phase generally spans a duration of 3 to 6 months. Following the build-up phase, patients transition to the maintenance phase, which involves monthly injections that can continue for an extended period of 3 to 5 years. The allergenic extract utilized in this therapy is prepared and provided by the physician or another qualified healthcare professional, ensuring that the treatment is both safe and effective. For billing purposes, CPT® Code 95132 specifically applies to the administration of allergen immunotherapy involving three stinging insect venoms, with additional codes available for varying numbers of venoms administered.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 95132 is indicated for patients who have been diagnosed with allergies to stinging insects, which may include various species such as bees, wasps, hornets, or yellow jackets. The following conditions warrant the use of allergen immunotherapy:

  • Allergic Reactions to Stinging Insects Patients who experience significant allergic reactions, such as anaphylaxis or severe localized reactions, upon exposure to stinging insects.
  • Positive Allergy Testing Individuals who have undergone allergy testing that confirms sensitivity to one or more stinging insect venoms.
  • History of Severe Allergic Reactions Patients with a documented history of severe allergic reactions to stings, which may include symptoms such as difficulty breathing, swelling, or hives.

2. Procedure

The procedure for allergen immunotherapy as per CPT® Code 95132 involves several key steps that ensure the safe and effective administration of the treatment:

  • Step 1: Allergy Testing Prior to initiating immunotherapy, patients must undergo allergy testing to identify specific stinging insect allergens. This testing is crucial for determining the appropriate allergenic extracts to be used in the immunotherapy regimen.
  • Step 2: Development of Immunotherapy Schedule Based on the results of the allergy testing, a personalized immunotherapy schedule is created. This schedule outlines the build-up phase and the maintenance phase, detailing the frequency and dosage of allergenic extracts to be administered.
  • Step 3: Build-Up Phase Administration During the build-up phase, patients receive injections of the allergenic extract(s) in gradually increasing doses. These injections are typically administered in the upper arm and occur one to three times per week over a period of 3 to 6 months. This phase is critical for developing tolerance to the allergens.
  • Step 4: Transition to Maintenance Phase After the build-up phase, patients transition to the maintenance phase, which involves monthly injections of the allergenic extract(s). This phase can last for 3 to 5 years, providing ongoing exposure to the allergens to maintain desensitization.
  • Step 5: Monitoring and Follow-Up Throughout the treatment process, patients are monitored for any adverse reactions or side effects. Follow-up appointments are essential to assess the effectiveness of the therapy and make any necessary adjustments to the treatment plan.

3. Post-Procedure

Post-procedure care following allergen immunotherapy involves several considerations to ensure patient safety and treatment efficacy. Patients are typically advised to remain in the office for a short period after receiving their injection to monitor for any immediate allergic reactions. It is important for patients to report any unusual symptoms, such as swelling, difficulty breathing, or hives, to their healthcare provider promptly. Additionally, patients may be instructed to avoid strenuous activities for a short time following the injection. Regular follow-up appointments are necessary to evaluate the patient's response to the therapy and to adjust the treatment plan as needed. Over the course of the maintenance phase, patients should continue to adhere to their scheduled injection appointments to maintain the benefits of desensitization.

Short Descr IMMNTX 3 STING INSECTS
Medium Descr PROF SVCS ALLG IMMNTX W/PRV XTRC 3 STING INSECT
Long Descr Professional services for allergen immunotherapy in the office or institution of the prescribing physician or other qualified health care professional, including provision of allergenic extract; 3 stinging insect venoms
Status Code Not Valid for Medicare Purposes
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Non-Covered Service, not paid under OPPS
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) M5D - Specialist - other
MUE 0
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Date
Action
Notes
2013-01-01 Changed Description Changed
2011-01-01 Changed Short description changed.
2009-01-01 Changed Code description changed
Pre-1990 Added Code added.
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