Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account

Need help choosing the right code?

Ask CasePilot about procedures, modifiers, bundling, and coding guidance.

Try CasePilot
Code deleted, see 89337 or use 0357T.

Official Description

Cryopreservation; oocyte(s)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 0059T refers to the process of cryopreservation specifically for oocytes, which are the female reproductive cells or eggs. This procedure is typically performed during a separate, reportable medical intervention where ovarian reproductive tissue or individual oocytes are harvested for the purpose of preserving them for future use in assisted reproductive technologies. The cryopreservation process involves several critical steps to ensure the viability of the oocytes when they are thawed for later fertilization. Initially, the harvested oocytes undergo a thorough assessment to determine their quality and readiness for freezing. Following this evaluation, a series of specialized cryoprotectant solutions are prepared, which are essential for protecting the oocytes during the freezing process. The cryoprotectants help to prevent the formation of ice crystals within the cells, which can cause damage. There are two primary techniques utilized for the freezing of oocytes: the traditional slow freezing method and a more advanced rapid freezing technique known as vitrification. The slow freezing method involves gradually cooling the oocytes in a controlled manner, while vitrification employs a high concentration of cryoprotectant to achieve a rapid solidification of the oocytes into a glass-like state, effectively eliminating ice crystal formation. Once the oocytes are frozen using either method, they are stored in a controlled environment, typically in liquid nitrogen, until they are required for use in future assisted reproduction procedures. This meticulous process ensures that the oocytes remain viable and can be successfully utilized when needed, thereby enhancing the chances of successful fertilization and pregnancy in subsequent assisted reproductive efforts.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The cryopreservation of oocytes is indicated for various scenarios where preservation of female reproductive potential is desired. The following conditions may warrant this procedure:

  • Fertility Preservation - Women undergoing medical treatments such as chemotherapy or radiation therapy that may adversely affect ovarian function may choose to preserve their oocytes for future use.
  • Advanced Maternal Age - Women of advanced reproductive age may opt for oocyte cryopreservation to enhance their chances of conception at a later time when they may be ready to start a family.
  • Ovarian Surgery - Patients requiring surgical procedures on the ovaries may have their oocytes cryopreserved prior to surgery to safeguard their fertility.
  • Genetic Conditions - Women with known genetic disorders may choose to cryopreserve oocytes to ensure that they can have children without passing on hereditary conditions.

2. Procedure

The procedure for cryopreservation of oocytes involves several detailed steps to ensure the successful preservation of the reproductive cells. The following outlines the procedural steps:

  • Step 1: Oocyte Retrieval - The first step involves the surgical retrieval of oocytes from the ovaries. This is typically performed under sedation or anesthesia, where a transvaginal ultrasound-guided needle is used to aspirate the oocytes from the ovarian follicles.
  • Step 2: Assessment of Oocytes - Once retrieved, the oocytes are carefully assessed for quality and maturity. Only those that meet specific criteria for viability are selected for the cryopreservation process.
  • Step 3: Preparation of Cryoprotectant Solutions - A series of cryoprotectant solutions are prepared, which are crucial for protecting the oocytes during freezing. These solutions are designed to minimize ice crystal formation and cellular damage.
  • Step 4: Freezing Process - The selected oocytes are subjected to either the slow freezing method or the vitrification technique. In the slow freezing method, the oocytes are gradually cooled, while in vitrification, they are rapidly frozen using a high concentration of cryoprotectant to achieve a glass-like state.
  • Step 5: Storage - After freezing, the oocytes are placed in labeled straws or vials containing identifying information, including the patient’s name and the contents. They are then stored in a controlled environment, either in vapor phase or submerged in liquid nitrogen, until they are needed for future assisted reproduction procedures.

3. Post-Procedure

Post-procedure care for patients undergoing oocyte cryopreservation typically involves monitoring for any immediate complications related to the retrieval process. Patients may experience mild discomfort, cramping, or spotting following the procedure. It is essential for patients to follow up with their healthcare provider to discuss the results of the oocyte assessment and to receive guidance on future fertility options. The stored oocytes can remain viable for many years, allowing patients the flexibility to plan for future pregnancies when they are ready. Proper documentation and tracking of the stored oocytes are crucial for ensuring their safe retrieval and use in subsequent assisted reproduction procedures.

Short Descr CRYOPRESERVATION OOCYTE
Medium Descr CRYOPRESERVATION OOCYTES
Long Descr Cryopreservation; oocyte(s)
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Ancillary Services
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 235 - Other Laboratory
Date
Action
Notes
2015-01-01 Deleted Code deleted, see 89337 or use 0357T.
2011-01-01 ReActivated Reactivated
2011-01-01 Added Code added.
2009-01-01 Deleted -
2004-01-01 Added First appearance in code book in 2004.
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"