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Official Description

Holotranscobalamin, quantitative

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 0103T refers to the quantitative measurement of holotranscobalamin, a form of vitamin B12 that is biologically active and available for cellular uptake. This test involves analyzing a blood sample to quantify the levels of holotranscobalamin present in the bloodstream. Holotranscobalamin is significant because it serves as a marker for vitamin B12 status in the body. Abnormal levels of holotranscobalamin can suggest a deficiency in vitamin B12, which is essential for various bodily functions, including red blood cell formation, neurological function, and DNA synthesis. The assessment of holotranscobalamin levels is particularly useful in diagnosing and monitoring conditions related to vitamin B12 deficiency, allowing healthcare providers to make informed decisions regarding patient management and treatment options.

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