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Official Description

Procalcitonin (PCT)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A procalcitonin (PCT) test is a diagnostic procedure that measures the level of procalcitonin in the blood serum. Procalcitonin is a peptide that is produced by the body in response to bacterial infections, making it a highly specific biomarker for the early detection and therapeutic monitoring of clinically significant bacterial infections or sepsis. The presence of elevated procalcitonin levels in the bloodstream serves as an indicator not only of the existence of a bacterial infection but also of its severity. This test is particularly valuable in clinical settings as it aids healthcare providers in distinguishing between bacterial infections and viral infections or other forms of nonbacterial inflammation. The procedure involves obtaining a blood sample through a process known as venipuncture, which is separately reportable. The analysis of the blood sample is conducted using immunofluorescence techniques to accurately determine the serum concentrations of procalcitonin, thereby providing critical information for patient management and treatment decisions.

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