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Official Description

Stereotactic placement of infusion catheter(s) in the brain for delivery of therapeutic agent(s), including computerized stereotactic planning and burr hole(s)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 0169T involves the stereotactic placement of infusion catheters in the brain, which facilitates the delivery of therapeutic agents directly to targeted areas within the central nervous system. This method is particularly advantageous due to the presence of the blood-brain barrier (BBB), a selective permeability barrier that restricts the passage of many pharmaceutical agents from the bloodstream into the brain. By utilizing a stereotactic approach, healthcare professionals can precisely navigate to specific brain regions, ensuring that therapeutic agents are administered effectively. The procedure begins with advanced imaging techniques, such as MRI or CT scans, which are employed to visualize the brain and assist in the meticulous planning of catheter placement. Surgical planning software is utilized to create a detailed algorithm that guides the placement of burr holes and catheters. During the procedure, an incision is made in the scalp to access the skull, and an air-powered drill is used to create burr holes through which the catheters are inserted. These catheters are then carefully threaded into the brain, guided by real-time imaging, and secured in place. Once the catheters are positioned, the scalp is closed around them, and the infusion of therapeutic agents begins. This technique is particularly beneficial for treating various conditions, including tumors and neurodegenerative diseases such as progressive multifocal leukoencephalopathy, Gaucher's disease, and Parkinson's disease, as well as neurological disorders like epilepsy. The ability to deliver drugs directly to the brain enhances their efficacy and minimizes systemic side effects, making this procedure a critical option in the management of complex neurological conditions.

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