CPT® Code 0423T

Deleted

A laboratory test is conducted to assess the circulating levels of secretory type II phospholipase A2 (sPLA2-IIA) in plasma. This enzyme is part of the phospholipase A2 family, which plays a crucial role in the hydrolysis of phospholipids, resulting in the production of pro-inflammatory lysophospholipids and fatty acids. Elevated levels of sPLA2-IIA are frequently associated with conditions such as coronary artery disease (CAD) and atherosclerosis, making this test significant in the context of cardiovascular health. The measurement of sPLA2-IIA levels can be utilized alongside clinical evaluations and risk assessment tools to estimate an individual's risk for CAD before a cardiovascular event occurs. Additionally, this test serves as a predictive measure for the likelihood of recurrent cardiac events or sudden cardiac death, particularly in patients who have experienced acute myocardial infarction or unstable angina. To perform this test, a blood sample is collected through a separately reportable venipuncture, and the plasma is analyzed using the enzyme-linked immunosorbent assay (ELISA) method.