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Code deleted, see 81200-81479

Official Description

Molecular diagnostics; nucleic acid probe, each

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83896 refers to a specific molecular diagnostic procedure that involves the use of nucleic acid probes. In this context, a molecular sequence is extracted from a tissue sample, which can be derived from various sources such as blood, biopsies, or other bodily fluids. The primary purpose of utilizing nucleic acid probes is to track and identify infectious diseases present within the extracted sample sequence. This technique is particularly valuable as it allows for the detection of genetic mutations that may indicate the presence of certain diseases, even in cases where the patient does not exhibit any symptoms. By analyzing the nucleic acids, healthcare professionals can gain insights into the genetic makeup of pathogens or the host's response, thereby facilitating early diagnosis and targeted treatment strategies. This procedure plays a crucial role in modern diagnostics, especially in the fields of oncology, infectious diseases, and genetic disorders.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 83896 is indicated for various clinical scenarios where the identification of infectious diseases or genetic mutations is necessary. The following conditions may warrant the use of this molecular diagnostic technique:

  • Infectious Disease Detection This procedure is utilized to identify the presence of infectious agents within a tissue sample, aiding in the diagnosis of diseases that may not present with overt symptoms.
  • Genetic Mutation Analysis It assists in detecting specific genetic mutations that could be indicative of certain diseases, allowing for early intervention and management.
  • Asymptomatic Screening The procedure can be performed on individuals who do not show symptoms but may be at risk for certain genetic conditions or infections.

2. Procedure

The procedure for CPT® Code 83896 involves several critical steps to ensure accurate molecular diagnostics. Each step is essential for the successful extraction and analysis of nucleic acids from the tissue sample.

  • Step 1: Sample Collection A tissue sample is collected from the patient, which may include blood, biopsy, or other bodily fluids. The collection method is crucial as it must preserve the integrity of the nucleic acids for subsequent analysis.
  • Step 2: Nucleic Acid Extraction The collected sample undergoes a process to extract nucleic acids, which may involve chemical or enzymatic methods to break down cellular components and isolate DNA or RNA.
  • Step 3: Probe Hybridization Nucleic acid probes are introduced to the extracted nucleic acids. These probes are designed to bind specifically to target sequences associated with infectious agents or genetic mutations, facilitating their identification.
  • Step 4: Detection and Analysis The binding of the probes to the target sequences is detected using various techniques, such as fluorescence or other signal amplification methods. This step allows for the visualization and quantification of the nucleic acids of interest.
  • Step 5: Interpretation of Results The results are analyzed by qualified personnel, who interpret the data to determine the presence of infectious diseases or genetic mutations, providing critical information for diagnosis and treatment planning.

3. Post-Procedure

After the completion of the procedure associated with CPT® Code 83896, the patient may not require extensive post-procedure care, as the process is typically minimally invasive. However, it is essential to monitor the patient for any immediate reactions to the sample collection. The results of the molecular diagnostic test will be communicated to the healthcare provider, who will discuss the findings with the patient and outline any necessary follow-up actions or treatments based on the results. Additionally, proper documentation of the procedure and results is crucial for compliance and future reference.

Short Descr MOLECULAR DIAGNOSTICS
Medium Descr MOLECULAR DIAGNOSTICS
Long Descr Molecular diagnostics; nucleic acid probe, each
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Discontinued Code
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
Date
Action
Notes
2013-01-01 Deleted Code deleted, see 81200-81479
2013-01-01 Changed Short and Medium Descriptors changed.
1993-01-01 Added Code added.
Code
Description
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