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Code deleted, see 81200-81479

Official Description

Molecular diagnostics; interpretation and report

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83912 refers to the process of molecular diagnostics, specifically focusing on the interpretation and report of molecular sequences extracted from tissue samples. This procedure involves analyzing genetic material to identify specific sequences that may be relevant for diagnosing diseases, understanding genetic conditions, or guiding treatment decisions. The interpretation of these molecular sequences is crucial as it provides healthcare professionals with insights into the genetic makeup of the tissue, which can influence patient management and therapeutic strategies. The report generated from this interpretation serves as a formal documentation of the findings, summarizing the results and their potential implications for the patient's health. This process is essential in the field of personalized medicine, where treatment plans can be tailored based on the unique genetic profile of an individual.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 83912 is indicated for various clinical scenarios where molecular diagnostics can provide valuable insights. These indications may include:

  • Genetic Disorders Identification of specific genetic mutations or alterations that may be responsible for inherited conditions.
  • Cancer Diagnosis Analysis of tumor samples to detect genetic changes that could inform diagnosis, prognosis, and treatment options.
  • Infectious Diseases Detection of pathogens through their genetic material, aiding in the diagnosis of infections.
  • Pharmacogenomics Understanding how genetic variations affect individual responses to medications, which can guide personalized treatment plans.

2. Procedure

The procedure for CPT® Code 83912 involves several critical steps to ensure accurate interpretation and reporting of molecular sequences. These steps include:

  • Sample Collection A tissue sample is obtained from the patient, which may involve a biopsy or other methods of tissue acquisition. This sample serves as the source of genetic material for analysis.
  • DNA/RNA Extraction The molecular sequences are extracted from the collected tissue sample. This process involves isolating the DNA or RNA, which is essential for subsequent analysis.
  • Sequencing The extracted genetic material undergoes sequencing to determine the specific order of nucleotides. This step is crucial for identifying any mutations or variations present in the sample.
  • Data Analysis The sequenced data is analyzed using bioinformatics tools to interpret the genetic information. This analysis helps in identifying significant genetic alterations that may be clinically relevant.
  • Report Generation A comprehensive report is created, summarizing the findings of the molecular analysis. This report includes interpretations of the results and their potential implications for patient care.

3. Post-Procedure

After the completion of the molecular diagnostics procedure associated with CPT® Code 83912, the patient may not require any specific post-procedure care related to the molecular testing itself. However, it is essential for healthcare providers to discuss the results of the interpretation and report with the patient. This discussion may include the implications of the findings, potential treatment options, and any further testing that may be necessary based on the results. Additionally, follow-up appointments may be scheduled to monitor the patient's condition and response to any initiated treatments based on the molecular diagnostic findings.

Short Descr GENETIC EXAMINATION
Medium Descr GENETIC EXAMINATION
Long Descr Molecular diagnostics; interpretation and report
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 6 - Laboratory Physician Interpretation Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Discontinued Code
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
Date
Action
Notes
2013-01-01 Deleted Code deleted, see 81200-81479
2013-01-01 Changed Short and Medium Descriptors changed.
Pre-1990 Added Code added.
Code
Description
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