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Official Description

Immune globulin (Ig), human, for intramuscular use

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Immune globulins are specialized immunizing agents that provide effective, short-term, passive immunity to individuals. This type of immunity is characterized by the presence of antibodies that circulate throughout the body, offering immediate protection against certain infections. Unlike active immunity, where the recipient's immune system is stimulated to produce its own antibodies, passive immunity does not involve this process. Instead, it relies on the administration of human immune globulin, which is a concentrated solution of antibodies derived from the pooled blood of multiple donors. The specific CPT® Code 90281 refers to human immune globulin (Ig) that is administered via intramuscular injection. It is important to note that this code solely represents the product used, and does not encompass any additional procedures or services associated with its administration. For intravenous administration of immune globulin, the corresponding code is 90283.

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