CPT® Code 90386

The Rho(D) immune globulin (RhIgIV) is a specialized immunizing agent that is administered intravenously. It consists of a concentrated solution of antibodies specifically designed to provide short-term, passive immunity to individuals. This means that the immune globulin offers immediate protection without stimulating the recipient's immune system to produce its own antibodies. The primary function of this passive immunity is to prevent adverse blood reactions that can occur when Rh-positive red blood cells interact with Rh-negative red blood cells, a situation that can arise during pregnancy or blood transfusions. The immune globulin is sourced from the pooled blood of multiple donors, ensuring a broad spectrum of antibodies. It is important to note that this code, CPT® 90386, specifically pertains to the intravenous formulation of human Rho(D) immune globulin, distinguishing it from other related codes such as 90384, which covers the intramuscular use, and 90385, which refers to a mini dose of the intramuscular formulation. These codes are strictly for reporting the product used and do not encompass any additional procedures or services associated with its administration.