CPT® Code 90288

The CPT® Code 90288 refers to botulism immune globulin, human, specifically formulated for intravenous use. This immunizing agent is designed to provide effective, short-term passive immunity against botulism, a serious illness caused by toxins produced by the bacterium Clostridium botulinum. Unlike active immunization, where the recipient's immune system is stimulated to produce its own antibodies, passive immunity involves the direct transfer of antibodies from another source. In this case, the antibodies are derived from pooled donor blood from individuals who have already developed immunity to botulism. As a result, the recipient receives immediate protection without the need for their immune system to respond. This code is utilized solely to report the administration of the human botulism immune globulin product for intravenous use, ensuring accurate documentation and billing for this specific therapeutic intervention.