© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 90389 refers to Tetanus immune globulin (TIg), which is a human-derived immunizing agent administered via intramuscular injection. This product is a concentrated solution containing antibodies specifically designed to provide short-term, passive immunity against tetanus. Unlike active immunization, where the recipient's immune system is stimulated to produce its own antibodies, the administration of TIg offers immediate protection by supplying pre-formed antibodies directly into the bloodstream. These antibodies are harvested from the pooled blood of multiple donors who have previously developed immunity to tetanus, ensuring a robust source of protection. The use of this code is strictly for reporting the human tetanus immune globulin product itself, emphasizing its role in providing passive immunity rather than stimulating the body's own immune response.
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