© Copyright 2026 American Medical Association. All rights reserved.
Thoracentesis, as described by CPT® Code 32421, is a medical procedure that involves the puncture of the pleural cavity for the purpose of aspiration, which can be either initial or subsequent. This procedure is performed to remove excess fluid or air that has accumulated in the pleural space, the area between the lungs and the chest wall. Prior to the procedure, the skin over the puncture site is thoroughly cleaned and a local anesthetic is administered to minimize discomfort for the patient. To enhance the accuracy of needle placement, imaging guidance techniques such as ultrasound, fluoroscopy, or computed tomography (CT) may be utilized, although these are reported separately. During the procedure, the physician carefully inserts a needle between the ribs into the pleural cavity, allowing for the withdrawal of fluid or air. This code is applicable for both the initial aspiration and any subsequent aspirations that may be necessary. It is important to note that this procedure is distinct from the insertion of a chest tube, which is coded separately under CPT® Code 32422, where a more invasive approach is taken to manage pleural effusions or pneumothorax.
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