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The CPT® Code 80348 refers to a laboratory test specifically designed to measure the levels of buprenorphine and its metabolites in biological samples such as urine, serum, or plasma. Buprenorphine is classified as a semi-synthetic opioid partial agonist, which means it activates opioid receptors in the brain but to a lesser degree than full agonists. This property makes it particularly useful in the treatment of opioid addiction, as it can help manage withdrawal symptoms and cravings without producing the same level of euphoria associated with stronger opioids. Additionally, buprenorphine is utilized for controlling acute or chronic pain in individuals who are not tolerant to opioids. The medication is available in various formulations, including oral tablets (such as Subutex, Suboxone, and Zubsolv) for the treatment of opioid dependence, and sublingual preparations (like Temgesic) for managing moderate to severe pain. For acute pain management, buprenorphine can be administered via injection (Buprenex), while chronic pain may be treated with transdermal patches (Norspan, Butrans) that deliver the drug through the skin over an extended period. To perform the test, a blood sample is typically obtained through venipuncture, which is a separately reportable procedure. Urine samples can be collected either by random voiding or through catheterization. The testing process involves advanced techniques such as quantitative high-performance liquid chromatography-tandem mass spectrometry for serum or plasma samples, and quantitative liquid chromatography-tandem mass spectrometry for urine samples. These methods ensure accurate measurement of buprenorphine levels, which is essential for monitoring treatment efficacy and compliance in patients undergoing therapy for opioid addiction or pain management.
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The laboratory test associated with CPT® Code 80348 is indicated for the following conditions:
The procedure for conducting the buprenorphine test involves several key steps, which are detailed as follows:
After the completion of the buprenorphine testing procedure, the samples are analyzed, and the results are typically available within a specified timeframe, depending on the laboratory's processing capabilities. Healthcare providers will review the test results to determine the appropriate course of action for the patient, which may include adjustments to the treatment plan based on the buprenorphine levels detected. It is essential for healthcare professionals to communicate the results to the patient and discuss any necessary follow-up actions or additional testing that may be required. Proper documentation of the test results and any subsequent decisions made is crucial for maintaining compliance and ensuring continuity of care.
| Short Descr | DRUG SCREENING BUPRENORPHINE | Medium Descr | DRUG SCREENING BUPRENORPHINE | Long Descr | Buprenorphine | Status Code | Not Valid for Medicare Purposes | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | Code Not Recognized by OPPS when submitted on Outpatient Hospital Part B Bill Type (12x/13x) | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T2D - Other tests - other | MUE | 1 |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | 26 | Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number. | 59 | Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25. |
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| 2015-01-01 | Added | Added |
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