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The CPT® Code 80354 refers to a laboratory test specifically designed to measure the levels of fentanyl in biological specimens such as urine, serum, or plasma. Fentanyl is classified as a potent synthetic opioid analgesic, known for its rapid onset of action and relatively short duration. This medication is frequently utilized in conjunction with benzodiazepines to facilitate conscious sedation during various medical procedures. Clinically, fentanyl is indicated for the management of acute postoperative pain, as well as breakthrough pain that may occur in patients with cancer or those suffering from bone fractures. Additionally, it is employed in the treatment of chronic pain conditions. Fentanyl can be administered through various routes, including intravenously (under the brand name Sublimaze), intrathecally in conjunction with spinal or epidural anesthesia, via a transdermal patch (known as Duragesic), and orally in several forms such as a lollipop or lozenge (Actiq), buccal tablet (Fentora), or sublingual spray. The collection of a blood sample for this test is performed through a separately reportable venipuncture, while urine specimens can be obtained either by random voiding or catheterization. The testing of urine, serum, and plasma for fentanyl levels is conducted using quantitative liquid chromatography-tandem mass spectrometry, a highly sensitive and specific analytical technique.
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The laboratory test for fentanyl is indicated for the following conditions:
The procedure for measuring fentanyl levels involves several key steps:
After the procedure, the collected specimens are sent to the laboratory for analysis. Results are typically reported back to the healthcare provider, who will interpret the findings in the context of the patient's clinical situation. It is important to monitor the patient's response to fentanyl therapy, especially in cases of acute postoperative pain or chronic pain management, to ensure that the medication is effective and to adjust dosages as necessary. Additionally, healthcare providers should be aware of the potential for fentanyl-related side effects and monitor patients accordingly.
| Short Descr | DRUG SCREENING FENTANYL | Medium Descr | DRUG SCREENING FENTANYL | Long Descr | Fentanyl | Status Code | Not Valid for Medicare Purposes | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | Code Not Recognized by OPPS when submitted on Outpatient Hospital Part B Bill Type (12x/13x) | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T2D - Other tests - other | MUE | 1 |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | GZ | Item or service expected to be denied as not reasonable and necessary |
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| 2015-01-01 | Added | Added |
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