CPT® Code 80365

A laboratory test identified by CPT® Code 80365 is specifically designed to measure the presence and concentration of oxycodone, a semi-synthetic opioid, in biological samples such as urine, serum, or plasma. Oxycodone is classified as a narcotic analgesic and is commonly utilized in the management of moderate to severe acute or chronic pain. This medication can be administered independently or in conjunction with other analgesics, such as aspirin or acetaminophen, to enhance pain relief. The administration of oxycodone can occur through various routes, including oral ingestion or injection. To perform this test, a blood sample is typically collected via venipuncture, which is a separate procedure that must be reported independently. Alternatively, urine samples can be obtained through random voiding or catheterization. The testing process involves screening urine samples using a qualitative enzyme immunoassay, while urine, serum, and plasma samples are analyzed quantitatively using liquid chromatography-tandem mass spectrometry, a highly sensitive and specific method for detecting and quantifying substances in biological fluids.