CPT® Code 80366

The CPT® Code 80366 refers to a laboratory test specifically designed to measure the levels of pregabalin in biological samples such as urine, serum, or plasma. Pregabalin, which is commercially known as Lyrica, is classified as an anticonvulsant medication. It is primarily prescribed for the management of neuropathic pain, which includes conditions like post-herpetic neuralgia and diabetic peripheral neuropathy. Additionally, pregabalin is utilized in the treatment of chronic pain disorders, including fibromyalgia. Furthermore, it serves as an adjunctive therapy for patients diagnosed with partial seizure disorders, whether or not these seizures progress to secondary generalization. The testing process involves obtaining a blood sample through a procedure known as venipuncture, which is separately reportable, while urine samples can be collected via random voiding or catheterization. The analysis of urine, serum, and plasma samples is conducted using a sophisticated technique known as quantitative high performance liquid chromatography coupled with tandem mass spectrometry, which allows for precise measurement of pregabalin levels in the samples collected.