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Official Description

Methylphenidate

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A laboratory test identified by CPT® Code 80360 is specifically designed to measure the levels of methylphenidate and its metabolite, ritalinic acid, in the body. Methylphenidate, commonly known by brand names such as Ritalin, Methylin, and Concerta, is classified as a central nervous system psycho-stimulant. This medication is primarily utilized in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and postural orthostatic tachycardia syndrome. The mechanism of action for methylphenidate involves the enhancement of neurotransmitter levels, particularly dopamine and norepinephrine, within the brain. This increase facilitates improved focus and better control over actions for individuals who may struggle with attention and impulse regulation. The testing process involves obtaining a blood sample through a venipuncture, which is a procedure that can be reported separately, as well as collecting urine either through random voiding or catheterization. The analysis of urine, serum, and plasma samples is conducted using a sophisticated technique known as quantitative liquid chromatography-tandem mass spectrometry, which allows for precise measurement of the substances in question.

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