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CPT®
80360

CPT® Code 80360

Official Description

Methylphenidate

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A laboratory test identified by CPT® Code 80360 is specifically designed to measure the levels of methylphenidate and its metabolite, ritalinic acid, in the body. Methylphenidate, commonly known by brand names such as Ritalin, Methylin, and Concerta, is classified as a central nervous system psycho-stimulant. This medication is primarily utilized in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and postural orthostatic tachycardia syndrome. The mechanism of action for methylphenidate involves the enhancement of neurotransmitter levels, particularly dopamine and norepinephrine, within the brain. This increase facilitates improved focus and better control over actions for individuals who may struggle with attention and impulse regulation. The testing process involves obtaining a blood sample through a venipuncture, which is a procedure that can be reported separately, as well as collecting urine either through random voiding or catheterization. The analysis of urine, serum, and plasma samples is conducted using a sophisticated technique known as quantitative liquid chromatography-tandem mass spectrometry, which allows for precise measurement of the substances in question.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The laboratory test associated with CPT® Code 80360 is indicated for the following conditions:

  • Attention Deficit Hyperactivity Disorder (ADHD) - This condition is characterized by persistent patterns of inattention and/or hyperactivity-impulsivity that interfere with functioning or development.
  • Narcolepsy - A chronic sleep disorder that causes overwhelming daytime drowsiness and sudden attacks of sleep.
  • Postural Orthostatic Tachycardia Syndrome (POTS) - A condition that affects the autonomic nervous system, leading to an abnormal increase in heart rate when transitioning to an upright position.

2. Procedure

The procedure for conducting the test under CPT® Code 80360 involves several key steps:

  • Step 1: Sample Collection - A blood sample is obtained through a procedure known as venipuncture, which involves inserting a needle into a vein to draw blood. This step is crucial as it provides the serum or plasma needed for analysis. Additionally, a urine sample is collected, which can be done either through random voiding or catheterization, depending on the clinical scenario and the patient's condition.
  • Step 2: Laboratory Analysis - Once the samples are collected, they are sent to a laboratory where they undergo testing. The analysis employs quantitative liquid chromatography-tandem mass spectrometry, a highly sensitive and specific method that allows for the accurate measurement of methylphenidate and its metabolite, ritalinic acid, in the collected samples. This technique is essential for determining the concentration of these substances in the body.

3. Post-Procedure

After the procedure, there are no specific post-procedure care requirements mentioned for the test associated with CPT® Code 80360. However, it is important for healthcare providers to monitor the patient’s response to methylphenidate therapy, especially in the context of the conditions being treated. The results of the test can provide valuable information regarding the effectiveness of the medication and help guide further treatment decisions.
Short Descr METHYLPHENIDATE
Medium Descr DRUG SCREENING METHYLPHENIDATE
Long Descr Methylphenidate
Status Code Not Valid for Medicare Purposes
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Code Not Recognized by OPPS when submitted on Outpatient Hospital Part B Bill Type (12x/13x)
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T2D - Other tests - other
MUE 1
Date
Action
Notes
2015-01-01 Added Added
Code
Description
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