CPT® Code 86723

The CPT® Code 86723 refers to a laboratory test specifically designed to measure antibodies against Listeria monocytogenes in both blood and cerebrospinal fluid (CSF). Listeria monocytogenes is a type of bacterium that is commonly found in various environments, including soil and water, and has the potential to contaminate food products such as raw fruits and vegetables, milk, and meat during their processing. This bacterium is notable for its ability to survive in refrigeration and freezing conditions, which poses a risk for foodborne illness. While L. monocytogenes typically causes mild gastrointestinal symptoms in healthy individuals, certain populations, including children, the elderly, and those with compromised immune systems, are at a heightened risk for more severe manifestations of the illness. Symptoms of listeriosis can include fever, muscle pain, nausea, diarrhea, headache, stiff neck, confusion, loss of balance, and seizures. Additionally, L. monocytogenes has the capability to cross the placenta, making pregnant women and their unborn children particularly susceptible to serious health complications. The testing process involves obtaining a blood sample through a separately reportable venipuncture and collecting CSF via a separately reportable lumbar puncture. The serum and CSF samples are then analyzed using a semi-quantitative complement fixation method to detect the presence of antibodies against the bacterium.