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Official Description

Antibody; mumps

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86735 refers to a laboratory test specifically designed to measure antibodies against the mumps virus in blood and/or cerebrospinal fluid (CSF). This test is crucial for diagnosing mumps, a highly contagious viral infection that presents with symptoms such as fever, headache, muscle aches, fatigue, decreased appetite, and notably, swollen parotid glands. The mumps virus is primarily transmitted through airborne respiratory droplets found in saliva and mucus, but it can also spread through the sharing of food, drinks, and eating utensils with an infected individual. The test evaluates two types of antibodies: IgM and IgG. A positive IgM antibody titer indicates either a current or recent infection or immunization against the mumps virus; however, it is important to note that low levels of IgM antibodies may persist for over 12 months following infection or immunization. Conversely, a positive IgG antibody titer suggests that the individual has either been exposed to the mumps virus in the past or has been immunized against it. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is reported separately, while CSF is obtained via a lumbar puncture, also reported separately. The testing methods employed include a semi-quantitative enzyme-linked immunosorbent assay for IgM antibodies and a semi-quantitative chemiluminescent immunoassay for IgG antibodies.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The mumps antibody test (CPT® Code 86735) is indicated for the following conditions:

  • Diagnosis of Mumps Infection This test is performed to confirm a suspected case of mumps based on clinical symptoms such as fever, headache, muscle aches, fatigue, decreased appetite, and swollen parotid glands.
  • Assessment of Immunity The test is used to determine an individual's immune status against the mumps virus, particularly in those who may have been exposed to the virus or have a history of vaccination.
  • Investigation of Outbreaks In the event of a mumps outbreak, this test can help identify infected individuals and assess the spread of the virus within a community.

2. Procedure

The procedure for conducting the mumps antibody test involves several key steps:

  • Step 1: Patient Preparation Prior to the test, the healthcare provider may provide instructions to the patient regarding any necessary preparations, such as fasting or avoiding certain medications that could affect test results.
  • Step 2: Sample Collection A blood sample is obtained through a process known as venipuncture, where a needle is inserted into a vein, typically in the arm, to draw blood. This procedure is reported separately. If cerebrospinal fluid (CSF) is required, a lumbar puncture is performed to collect the CSF, which is also reported separately.
  • Step 3: Laboratory Testing The collected serum and CSF samples are then sent to a laboratory for analysis. The laboratory employs a semi-quantitative enzyme-linked immunosorbent assay (ELISA) to test for IgM antibodies and a semi-quantitative chemiluminescent immunoassay to test for IgG antibodies against the mumps virus.
  • Step 4: Result Interpretation Once the testing is complete, the laboratory will interpret the results. A positive IgM titer indicates a current or recent infection or immunization, while a positive IgG titer suggests past exposure or immunization.

3. Post-Procedure

After the mumps antibody test is performed, patients may experience minor discomfort or bruising at the venipuncture site. If a lumbar puncture was conducted, patients may be advised to rest and drink plenty of fluids to help prevent headaches that can occur post-procedure. The healthcare provider will discuss the results with the patient once they are available, which may take several days. It is important for patients to follow up with their healthcare provider to understand the implications of the test results and any necessary next steps, especially if the results indicate a current infection or lack of immunity.

Short Descr MUMPS ANTIBODY
Medium Descr ANTIBODY MUMPS
Long Descr Antibody; mumps
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
1993-01-01 Added First appearance in code book in 1993.
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