CPT® Code 86744

The CPT® Code 86744 refers to a laboratory test specifically designed to measure antibodies against Nocardia, a genus of aerobic actinomycetes that are typically found in soil. This test is crucial for diagnosing infections caused by Nocardia species, particularly N. asteroides, which is the most frequently identified species associated with human infections. Nocardia infections can manifest in various forms, including acute, subacute, or chronic diseases, affecting both individuals with healthy immune systems and those who are immunocompromised. In healthy individuals, local infections, such as skin infections, are more common. Conversely, in those with weakened immune systems, Nocardia can lead to more severe disseminated infections, including pneumonia, sepsis, brain abscesses, eye infections, and joint infections. The laboratory test typically involves analyzing serum samples for IgG antibodies against Nocardia, employing methods such as complement fixation, enzyme immunoassay, or immunoblot techniques to detect the presence of these antibodies accurately.