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Official Description

Antibody; Nocardia

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86744 refers to a laboratory test specifically designed to measure antibodies against Nocardia, a genus of aerobic actinomycetes that are typically found in soil. This test is crucial for diagnosing infections caused by Nocardia species, particularly N. asteroides, which is the most frequently identified species associated with human infections. Nocardia infections can manifest in various forms, including acute, subacute, or chronic diseases, affecting both individuals with healthy immune systems and those who are immunocompromised. In healthy individuals, local infections, such as skin infections, are more common. Conversely, in those with weakened immune systems, Nocardia can lead to more severe disseminated infections, including pneumonia, sepsis, brain abscesses, eye infections, and joint infections. The laboratory test typically involves analyzing serum samples for IgG antibodies against Nocardia, employing methods such as complement fixation, enzyme immunoassay, or immunoblot techniques to detect the presence of these antibodies accurately.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The antibody test for Nocardia (CPT® Code 86744) is indicated for the following conditions:

  • Diagnosis of Nocardia Infection This test is performed to confirm the presence of antibodies in patients suspected of having a Nocardia infection, particularly in those exhibiting symptoms consistent with such infections.
  • Assessment of Immune Competence The test may be indicated in patients with compromised immune systems to evaluate their risk for disseminated Nocardia infections, which can lead to severe complications.
  • Monitoring Disease Progression In patients diagnosed with Nocardia infections, this test can be used to monitor the immune response and effectiveness of treatment over time.

2. Procedure

The procedure for testing Nocardia antibodies involves several key steps to ensure accurate results:

  • Sample Collection A serum sample is collected from the patient, typically through venipuncture. This sample serves as the basis for the antibody testing.
  • Serum Preparation The collected serum is processed to separate it from other blood components, ensuring that only the serum is used for the antibody testing.
  • Antibody Detection The laboratory employs specific techniques such as complement fixation, enzyme immunoassay, or immunoblot to detect the presence of IgG antibodies against Nocardia in the serum sample. Each method has its own procedural nuances, but all aim to accurately identify the antibodies indicative of infection.
  • Result Interpretation After the testing is completed, the results are analyzed and interpreted by laboratory professionals. Positive results indicate the presence of antibodies against Nocardia, suggesting an active or past infection, while negative results may suggest the absence of such an infection.

3. Post-Procedure

Post-procedure care for patients undergoing the Nocardia antibody test is generally minimal, as it is a laboratory test involving blood collection. Patients may be advised to hydrate adequately before the test to facilitate easier blood draw. After the blood sample is taken, there are typically no specific restrictions or requirements for the patient. However, it is essential for healthcare providers to communicate the importance of follow-up appointments to discuss test results and any necessary further actions based on the findings. In cases of positive results, additional diagnostic procedures or treatments may be warranted, and patients should be monitored for any symptoms of Nocardia infection.

Short Descr NOCARDIA ANTIBODY
Medium Descr ANTIBODY NOCARDIA
Long Descr Antibody; Nocardia
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
1993-01-01 Added First appearance in code book in 1993.
Code
Description
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