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Official Description

Typhoid vaccine, acetone-killed, dried (AKD), for subcutaneous use (U.S. military)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90693 refers to the Typhoid vaccine, specifically the acetone-killed, dried (AKD) formulation intended for subcutaneous administration, primarily utilized by the U.S. military. Vaccines, unlike immune globulins that offer short-term, passive immunity, are designed to provide active, long-term immunity. This is achieved by introducing altered versions of specific pathogens, such as viruses or bacteria, into the recipient's immune system. The immune system then responds by producing its own antibodies, which are crucial for defending against future infections by the same pathogen. In the case of typhoid fever, which is caused by the bacterium Salmonella typhi, symptoms can include high fever, rash, and diarrhea. The transmission of this disease typically occurs through the consumption of contaminated food, water, or milk. The CPT® coding system includes various codes for different types of typhoid vaccines, each offering distinct formulations and methods of administration. For instance, code 90690 is designated for an oral vaccine containing the live virus, while code 90691 is for the Vi capsular polysaccharide (ViCPs) vaccine administered via intramuscular injection. Code 90692 pertains to the heat- and phenol-inactivated (H-P) vaccine, which can be given subcutaneously or intradermally. In contrast, code 90693 specifically identifies the acetone-killed dried (AKD) vaccine, which is injected subcutaneously and is primarily used within military settings. It is important to note that these codes are strictly for reporting the specific vaccine product utilized in immunization against typhoid infection.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The Typhoid vaccine, acetone-killed, dried (AKD), is indicated for individuals who are at risk of exposure to Salmonella typhi, particularly in settings where the disease is prevalent. This vaccine is specifically recommended for members of the U.S. military who may be deployed to areas where typhoid fever is endemic. The vaccine serves to protect against the potential onset of typhoid fever, which can lead to severe health complications if contracted. It is essential for individuals traveling to regions with poor sanitation and hygiene practices to receive this vaccination to mitigate the risk of infection.

  • Risk of Exposure Individuals at risk of exposure to Salmonella typhi, especially in endemic areas.
  • Military Personnel Recommended for U.S. military members deployed to regions where typhoid fever is common.
  • Travelers Advisable for travelers to areas with inadequate sanitation and hygiene.

2. Procedure

The administration of the Typhoid vaccine, acetone-killed, dried (AKD), involves a series of procedural steps to ensure proper delivery and effectiveness of the vaccine. First, the healthcare provider must verify the patient's eligibility for vaccination, ensuring that there are no contraindications or allergies to the vaccine components. Following this, the provider prepares the vaccine by reconstituting the acetone-killed dried vaccine as per the manufacturer's instructions. This may involve adding a specific diluent to the vaccine vial and gently mixing it to ensure homogeneity. Once prepared, the provider selects an appropriate site for subcutaneous injection, typically in the upper arm or thigh, and cleans the area with an antiseptic wipe to minimize the risk of infection. The vaccine is then administered using a sterile syringe and needle, ensuring that the injection is delivered into the subcutaneous tissue. After the injection, the provider may apply gentle pressure to the injection site and cover it with a sterile bandage if necessary. Finally, the patient is monitored for a brief period to observe for any immediate adverse reactions, and they are provided with post-vaccination care instructions, including information on potential side effects and when to seek medical attention if needed.

  • Step 1: Verify Eligibility Confirm the patient's eligibility for vaccination, checking for contraindications or allergies.
  • Step 2: Prepare the Vaccine Reconstitute the acetone-killed dried vaccine according to the manufacturer's instructions.
  • Step 3: Select Injection Site Choose an appropriate site for subcutaneous injection, typically the upper arm or thigh.
  • Step 4: Administer the Vaccine Inject the vaccine into the subcutaneous tissue using a sterile syringe and needle.
  • Step 5: Monitor Patient Observe the patient for immediate adverse reactions and provide post-vaccination care instructions.

3. Post-Procedure

After the administration of the Typhoid vaccine, acetone-killed, dried (AKD), patients are typically advised to remain in the healthcare setting for a short period to monitor for any immediate adverse reactions, such as allergic responses or injection site reactions. Common side effects may include mild pain or swelling at the injection site, low-grade fever, or fatigue, which usually resolve on their own within a few days. Patients should be informed about these potential side effects and reassured that they are generally mild and temporary. Additionally, individuals are encouraged to keep the injection site clean and dry and to avoid strenuous activities that may irritate the area for a short time following the vaccination. It is also important for patients to be aware of the need for booster vaccinations as recommended, depending on their risk factors and the specific guidelines for typhoid vaccination. They should be instructed to seek medical attention if they experience any unusual or severe symptoms following the vaccination.

Short Descr TYPHOID VACCINE AKD SC
Medium Descr TYPHOID VACCINE AKD SUBQ U.S. MILITARY
Long Descr Typhoid vaccine, acetone-killed, dried (AKD), for subcutaneous use (U.S. military)
Status Code Excluded from Physician Fee Schedule by Regulation
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Code Not Recognized by OPPS when submitted on Outpatient Hospital Part B Bill Type (12x/13x)
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) O1G - Immunizations/Vaccinations
MUE Not applicable/unspecified.
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
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Action
Notes
2016-01-01 Deleted Deleted
2011-01-01 Changed Short description changed.
2004-01-01 Changed Code description changed.
1999-01-01 Added First appearance in code book in 1999.
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