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Official Description

Ethosuximide

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 80168 refers to a laboratory test specifically designed to measure the levels of ethosuximide in the blood. Ethosuximide, commonly known by its brand name Zarontin, is classified as an anticonvulsant medication primarily used in the management of seizures, particularly absence seizures. This blood test is crucial for monitoring the concentration of ethosuximide in patients who are undergoing treatment, as maintaining appropriate therapeutic levels is essential for the drug's efficacy and safety. The test is typically performed at the initiation of treatment, at regular intervals thereafter, and also during instances of breakthrough seizure activity, which may suggest that the blood levels of the medication have fallen below the therapeutic range. To conduct this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. Following the collection, the serum is analyzed using an enzyme immunoassay method, a sensitive technique that allows for accurate measurement of the drug concentration in the blood.

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