CPT® Code 80169

The CPT® Code 80169 refers to a laboratory test specifically designed to measure the levels of everolimus in the blood. Everolimus is an immunosuppressive medication that plays a critical role in preventing organ rejection in patients who have undergone kidney or liver transplants. It is marketed under various brand names, including Zortress and Certican. Additionally, everolimus is utilized in the treatment of certain types of cancers, such as advanced renal cell carcinoma (aRCC), subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC), progressive or metastatic pancreatic neuroendocrine tumors (PNET), and advanced hormone-receptor positive HER2-negative breast cancer in post-menopausal women, particularly when surgical options are not viable. To ensure therapeutic effectiveness and minimize potential toxicity, it is essential to monitor everolimus levels through pre-dose (trough) blood draws. The blood sample for this test is collected via venipuncture, which is a separately reportable procedure. The analysis of the blood is conducted using quantitative liquid chromatography-tandem mass spectrometry, a sophisticated technique that allows for precise measurement of drug concentrations in the bloodstream.