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Official Description

Haloperidol

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Haloperidol is a medication commonly used in the treatment of schizophrenia, a serious mental disorder characterized by distortions in thinking, perception, emotions, language, and sense of self. It is also utilized in managing symptoms associated with Tourette's syndrome, which includes involuntary tics and vocal utterances. The CPT® Code 80173 refers to a specific blood test that measures the level of haloperidol in the bloodstream. This monitoring is crucial as it helps healthcare providers determine the appropriate dosage of the medication for each patient, ensuring therapeutic effectiveness while minimizing the risk of toxicity. The test involves obtaining a blood specimen through a procedure known as venipuncture, which is separately reportable. The analysis of the blood serum or plasma is conducted using advanced techniques such as high-performance liquid chromatography (HPLC) or gas chromatography (GC), both of which are reliable methods for accurately quantifying drug levels in the body. Regular monitoring of haloperidol levels is essential for optimizing treatment outcomes and safeguarding patient health.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The haloperidol level monitoring test (CPT® Code 80173) is indicated for patients who are undergoing treatment with haloperidol. The specific indications for performing this test include:

  • Schizophrenia Monitoring the haloperidol level is essential for patients diagnosed with schizophrenia to ensure that the medication is effective and to adjust dosages as necessary.
  • Tourette's Syndrome This test is also indicated for individuals with Tourette's syndrome to manage symptoms effectively and prevent potential toxicity from the medication.

2. Procedure

The procedure for testing haloperidol levels involves several key steps, which are outlined as follows:

  • Step 1: Patient Preparation Prior to the blood draw, the patient may be instructed to avoid certain medications or substances that could interfere with the test results. It is important for the healthcare provider to review the patient's medication history and ensure that the patient is adequately informed about the procedure.
  • Step 2: Venipuncture A qualified healthcare professional performs venipuncture to obtain a blood specimen. This involves inserting a needle into a vein, typically in the arm, to collect the necessary blood sample. The site is cleaned with an antiseptic to reduce the risk of infection, and a tourniquet may be applied to make the vein more prominent.
  • Step 3: Sample Collection The blood is collected into a sterile tube, which is then labeled appropriately. The specimen must be handled with care to prevent contamination and ensure accurate results.
  • Step 4: Laboratory Analysis The collected blood serum or plasma is sent to a laboratory where it is analyzed using high-performance liquid chromatography (HPLC) or gas chromatography (GC). These methods are employed to accurately measure the concentration of haloperidol in the sample.
  • Step 5: Result Interpretation Once the analysis is complete, the laboratory provides the results to the healthcare provider, who will interpret the haloperidol levels in the context of the patient's treatment plan and make any necessary adjustments to the medication dosage.

3. Post-Procedure

After the blood specimen has been collected, there are generally no specific post-procedure care requirements for the patient. However, the patient may be advised to apply pressure to the venipuncture site to minimize bruising and bleeding. It is also important for the healthcare provider to discuss the expected timeline for receiving test results and any potential follow-up appointments to review the findings. Patients should be monitored for any adverse reactions to the blood draw, although such occurrences are rare. The results of the haloperidol level test will guide the ongoing management of the patient's treatment, ensuring that the medication remains effective and safe.

Short Descr ASSAY OF HALOPERIDOL
Medium Descr DRUG SCREEN QUANTITATIVE HALOPRIDOL
Long Descr Haloperidol
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GW Service not related to the hospice patient's terminal condition
Date
Action
Notes
2013-01-01 Changed Medium description changed per AMA 2013 corrections document dated January 25, 2013.
2001-01-01 Added First appearance in code book in 2001.
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