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Official Description

Quinidine

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 80194 refers to a laboratory test specifically designed to measure the levels of quinidine in the blood. Quinidine, which is also known by its brand names such as Cardioquin, Quinora, and Quinidex, is a medication that serves two primary pharmacological purposes. Firstly, it is utilized in the management of ventricular and atrial cardiac dysrhythmias, where it functions to block abnormal electrical impulses that can disrupt the normal rhythm of the heart. Secondly, quinidine is employed in the treatment of malaria, a serious infectious disease caused by parasites. The administration of quinidine can occur either orally or through injection, depending on the clinical scenario and the patient's needs. To ensure the drug is being used effectively and safely, healthcare providers monitor blood concentration levels of quinidine at regular intervals. This monitoring is crucial for assessing therapeutic drug levels, as it helps to determine whether the dosage is appropriate for the patient’s condition. The process of obtaining a blood sample for this test involves a venipuncture, which is a procedure that can be reported separately. Once the blood sample is collected, the serum is analyzed using a technique known as fluorescence polarization immunoassay, which allows for accurate measurement of quinidine levels in the bloodstream.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The following are the explicitly provided indications for performing the quinidine level test:

  • Cardiac Dysrhythmias The test is indicated for patients experiencing ventricular and atrial cardiac dysrhythmias, where monitoring quinidine levels is essential to ensure effective management of abnormal heart rhythms.
  • Malaria Treatment The test is also indicated for patients undergoing treatment for malaria, as monitoring quinidine levels can help assess the effectiveness of the therapy.

2. Procedure

The procedure for measuring quinidine levels involves several key steps that ensure accurate results. First, a healthcare professional will perform a venipuncture to obtain a blood sample from the patient. This step is critical as it allows for the collection of serum, which is necessary for the subsequent testing. The venipuncture is typically performed using a sterile needle and requires proper technique to minimize discomfort and ensure the integrity of the sample. Once the blood sample is collected, it is processed to separate the serum from the cellular components of the blood. The serum is then subjected to a fluorescence polarization immunoassay, a sophisticated laboratory technique that utilizes the principles of fluorescence to measure the concentration of quinidine in the serum. This method is known for its sensitivity and specificity, making it an effective choice for accurately determining drug levels. The results of this test will provide healthcare providers with essential information regarding the patient's quinidine levels, which can guide further treatment decisions.

3. Post-Procedure

After the blood sample has been collected and the test has been performed, there are generally no specific post-procedure care requirements for the patient. However, it is important for healthcare providers to monitor the patient’s response to quinidine therapy, especially if the levels are found to be outside the therapeutic range. Patients may be advised to report any unusual symptoms or side effects they experience following the administration of quinidine. Regular follow-up appointments may be scheduled to reassess quinidine levels and adjust dosages as necessary to ensure optimal therapeutic outcomes.

Short Descr ASSAY OF QUINIDINE
Medium Descr DRUG SCREEN QUANTITATIVE QUINIDINE
Long Descr Quinidine
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
2013-01-01 Changed Medium description changed per AMA 2013 corrections document dated January 25, 2013.
1993-01-01 Added First appearance in code book in 1993.
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Description
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Description
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