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The CPT® Code 80200 refers to the measurement of tobramycin levels in the blood. Tobramycin is classified as an injectable aminoglycoside antibiotic that is primarily utilized in the treatment of severe or serious bacterial infections. The measurement of tobramycin levels is critical due to the drug's potential side effects, which include auditory, vestibular, and renal toxicity. Monitoring these levels helps ensure that the drug is administered safely and effectively. The testing can be performed at various times, including random, peak, and trough levels. A random sample can be collected at any time, while peak and trough levels are specifically time-dependent. Typically, trough levels are drawn 5 to 90 minutes before the administration of the drug, either through intravenous infusion or intramuscular injection. Conversely, peak levels are collected 30 minutes after the completion of an intravenous infusion or 30 to 90 minutes following an intramuscular injection. The blood sample required for this test is obtained through a venipuncture, which is a separately reportable procedure. The analysis of the blood serum is conducted using a method known as fluorescence polarization immunoassay, which allows for accurate measurement of the tobramycin concentration in the bloodstream.
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