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CPT®
82646

CPT® Code 82646
Deleted

Code deleted, see 80361

Official Description

Dihydrocodeinone

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A laboratory test designated by CPT® Code 82646 is utilized to measure the concentration of dihydrocodeinone in the bloodstream. Dihydrocodeinone is a narcotic analgesic that shares a structural similarity with codeine, making it effective for managing moderate to severe pain and for cough suppression. This medication can be administered through oral ingestion or via injection, and it is frequently combined with other analgesics such as acetaminophen or aspirin to enhance its therapeutic effects. Dihydrocodeinone is commonly recognized under various brand names, including Vicodin, Lortab, and Tussionex. The testing process involves obtaining a blood sample through a procedure known as venipuncture, which is reported separately. The primary objective of this laboratory test is to quantify the level of dihydrocodeinone present in the sample, providing essential information for patient management and treatment decisions.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The laboratory test for dihydrocodeinone, coded as CPT® 82646, is indicated for the following conditions:

  • Moderate to Severe Pain This test is performed to monitor the levels of dihydrocodeinone in patients who are prescribed this medication for the management of moderate to severe pain.
  • Cough Control Dihydrocodeinone may also be indicated for patients experiencing severe cough, and this test helps in assessing the drug's concentration in the system.

2. Procedure

The procedure for testing dihydrocodeinone involves several key steps that ensure accurate measurement of the drug's level in the blood.

  • Step 1: Patient Preparation Prior to the blood draw, the patient may be instructed to avoid certain medications or substances that could interfere with the test results. It is essential to gather a thorough medical history to understand the patient's current medication regimen.
  • Step 2: Venipuncture A qualified healthcare professional performs venipuncture, which involves inserting a needle into a vein, typically in the arm, to collect a blood sample. This step is crucial as it must be done with precision to ensure an adequate volume of blood is obtained for testing.
  • Step 3: Sample Handling Once the blood sample is collected, it is properly labeled and handled according to laboratory protocols to prevent contamination or degradation of the sample. This may include placing the sample in a specific type of container and ensuring it is stored at the correct temperature.
  • Step 4: Laboratory Analysis The blood sample is then sent to a laboratory where it undergoes analysis to quantify the amount of dihydrocodeinone present. This process may involve various laboratory techniques to ensure accurate measurement.

3. Post-Procedure

After the blood sample has been collected, patients may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are generally no specific post-procedure care instructions required for this test, but patients should be advised to report any unusual symptoms or prolonged discomfort. The results of the dihydrocodeinone test will be interpreted by the healthcare provider, who will use this information to make informed decisions regarding the patient's treatment plan and medication management.
Short Descr ASSAY OF DIHYDROCODEINONE
Medium Descr ASSAY OF DIHYDROCODEINONE
Long Descr Dihydrocodeinone
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 9 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE Not applicable/unspecified.
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
Date
Action
Notes
2015-01-01 Deleted Code deleted, see 80361
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
Code
Description
Code
Description
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