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Official Description

Amphetamine or methamphetamine

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82145 refers to laboratory testing specifically for the presence of amphetamine or methamphetamine in biological samples. These substances are classified as psychostimulant drugs belonging to the phenethylamine class, which are known for their stimulating effects on the central nervous system. The testing can be conducted on various types of specimens, including urine, blood, or meconium stool, particularly in newborn infants. Amphetamines and methamphetamines are often associated with recreational use and are sometimes misused for enhancing athletic performance. However, they also have legitimate medical applications, as they may be prescribed to manage symptoms in individuals diagnosed with Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder (ADHD). The laboratory analysis typically involves obtaining a sample from the patient, which is then subjected to a sophisticated testing method known as quantitative liquid chromatography-tandem mass spectrometry. This method allows for precise measurement and identification of the substances in the sample, ensuring accurate results for clinical or forensic purposes.

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