CPT® Code 86606

The CPT® Code 86606 refers to the laboratory test for antibodies to Aspergillus, a type of fungus commonly found in various environments, including soil, decaying plant material, and certain food items. This test is performed on a blood or cerebrospinal fluid sample to detect the presence of antibodies that the immune system produces in response to Aspergillus infection. There are several species of Aspergillus, with A. fumigatus and A. flavus being the most prevalent. Infections caused by these fungi can lead to allergic bronchopulmonary disease, characterized by symptoms such as wheezing and coughing, although these conditions do not typically result in tissue damage. In contrast, more severe forms of infection, known as invasive aspergillosis, can occur, particularly in immunocompromised individuals. This serious condition primarily affects the lungs but can also impact other organs, including the central nervous system. Various testing methodologies are available to diagnose Aspergillus infections, including complement fixation, immunodiffusion, and enzyme-linked immunosorbent assay (ELISA). It is important to note that tests for Aspergillus typically measure IgG antibodies, and different methodologies may be employed to isolate these antibodies, with each method being reported separately.