CPT® Code 86696

The CPT® Code 86696 refers to the laboratory test for antibodies specific to herpes simplex virus type 2 (HSV-2). This test is performed on a sample of blood or cerebrospinal fluid to detect the presence of antibodies that indicate an immune response to HSV-2 infection. Herpes simplex virus is primarily transmitted through direct contact with an infected individual, and the initial infection often manifests as ulcerations on the skin or mucous membranes. After the primary infection, the virus can enter a dormant state within the body and may reactivate due to various triggers, including other illnesses, infections, or stress. Certain populations, such as neonates and individuals with compromised immune systems, are particularly vulnerable to severe complications, including ocular or central nervous system infections. Various testing methodologies are available for diagnosing HSV infections, including indirect hemagglutination (IHA), chemiluminescent immunoassay, and enzyme-linked immunosorbent assay (ELISA). The testing typically involves measuring immunoglobulin G (IgG) and immunoglobulin M (IgM) levels to confirm the presence of HSV infection. It is important to report each immunoglobulin class separately if both IgG and IgM tests are conducted. For non-specific HSV testing, the code 86694 is utilized, while code 86695 is designated for tests specific to HSV type 1. Code 86696 is specifically reserved for tests that identify antibodies related to HSV type 2, including glycoprotein G-specific antibody IgG and/or IgM testing.