CPT® Code 86695

The CPT® Code 86695 refers to the laboratory testing for antibodies specific to herpes simplex virus type 1 (HSV-1). This procedure involves analyzing a blood or cerebrospinal fluid sample to detect the presence of antibodies that indicate an immune response to HSV-1 infection. Herpes simplex virus is primarily transmitted through direct contact with an infected individual, and the initial infection often manifests as ulcerative lesions on the skin or mucous membranes. After the primary infection, the virus can enter a dormant or latent state within the body, remaining inactive until it is reactivated by various triggers such as other illnesses, infections, or stress. Certain populations, including neonates and individuals with compromised immune systems, are particularly vulnerable to severe complications from HSV-1, which can include infections of the eyes or central nervous system. To diagnose HSV infection, various testing methodologies are employed, including indirect hemagglutination (IHA), chemiluminescent immunoassay, and enzyme-linked immunosorbent assay (ELISA). The testing typically involves measuring two types of immunoglobulins: IgG and IgM. It is important to note that if both IgG and IgM tests are conducted, each test should be reported separately. For non-specific HSV testing, the code 86694 is utilized, while code 86695 is designated for tests specifically identifying HSV type 1. Conversely, code 86696 is used for tests that are specific to HSV type 2. Additionally, these codes can also be applied to report the presence of glycoprotein G-specific antibodies for both HSV type 1 and type 2, encompassing both IgG and IgM classes.