© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 86612 refers to the laboratory test for the detection of antibodies against Blastomyces, specifically targeting the fungus Blastomyces dermatitidis. This organism is typically found in soil and can lead to a serious infection known as blastomycosis when its spores are inhaled. The test is performed on a sample of blood or cerebral spinal fluid to identify the presence of antibodies that indicate an immune response to the infection. Blastomycosis can manifest in various forms, with acute infections often presenting flu-like symptoms such as fever, chills, myalgia, headache, and cough. In more severe cases, the acute infection may resemble bacterial pneumonia, characterized by a productive cough and significant respiratory distress. Chronic forms of the disease may lead to persistent low-grade fever, a productive cough, night sweats, and unintentional weight loss. Individuals with compromised immune systems are particularly vulnerable to disseminated blastomycosis, which can affect multiple organs, including the central nervous system. Various testing methods, such as complement fixation and immunodiffusion, are utilized to confirm the presence of Blastomyces infection, making this antibody test a critical component in the diagnosis and management of the disease.
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