© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 86622 refers to a laboratory test specifically designed to measure the presence of antibodies against the Brucella bacteria. Brucella is a genus of bacteria that primarily infects animals, particularly livestock, but can also infect humans, especially those who consume unpasteurized or raw dairy products. The transmission of Brucella to humans can occur through various routes, including ingestion, inhalation, or direct skin contact, which is particularly relevant for individuals in certain occupations such as veterinarians, hunters, laboratory personnel, and workers in meatpacking or slaughterhouse environments. Following exposure to the bacteria, symptoms of infection may manifest within a timeframe of 2 to 4 weeks. Common symptoms associated with brucellosis include fever, profuse sweating, headaches, muscle and joint pain, and general fatigue. The presence of a positive Brucella antibody titer is indicative of a brucellosis infection, particularly when accompanied by clinical symptoms and a documented history of potential exposure to the bacteria. To conduct this test, a blood sample is collected, which is reported separately as a venipuncture procedure. The serum obtained from the blood sample is then analyzed using a semi-quantitative agglutination method to determine the level of Brucella antibodies present.
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