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Official Description

Antibody; HIV-1 and HIV-2, single result

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86703 refers to the laboratory test for the detection of antibodies to both HIV-1 and HIV-2 in a single result. HIV, or Human Immunodeficiency Virus, is a virus that can lead to Acquired Immunodeficiency Syndrome (AIDS), a condition characterized by a severely weakened immune system. The virus is primarily transmitted through sexual contact, but it can also be spread through unscreened blood transfusions, sharing of needles, from mother to child during pregnancy or childbirth, and through breastfeeding. The immune system is compromised as HIV targets and destroys CD4 T cells, which are crucial for the body's ability to combat infections. The test associated with CPT® Code 86703 is a qualitative assessment, meaning it determines the presence or absence of antibodies specific to HIV-1 and/or HIV-2 in a blood sample. This test is essential for diagnosing HIV infections, allowing for timely intervention and management. It is important to note that this code is specifically used when both HIV-1 and HIV-2 antibodies are tested simultaneously, providing a comprehensive result in a single testing process. For more specific testing, separate codes are available: CPT® Code 86701 is used for HIV-1 antibody screening via a qualitative chemiluminescent immunoassay, while CPT® Code 86702 is designated for HIV-2 antibody screening using a qualitative enzyme immunoassay.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The CPT® Code 86703 is indicated for the detection of antibodies to HIV-1 and HIV-2 in individuals who may be at risk for HIV infection. The following conditions or situations warrant the use of this test:

  • High-Risk Sexual Behavior Individuals engaging in unprotected sexual intercourse with multiple partners or with partners of unknown HIV status.
  • Intravenous Drug Use Individuals who share needles or other drug paraphernalia, increasing the risk of HIV transmission.
  • Pregnancy Pregnant women, particularly those with risk factors, should be tested to prevent mother-to-child transmission of HIV.
  • Exposure to HIV Individuals who have had potential exposure to HIV through occupational hazards or sexual assault.
  • Routine Screening Individuals undergoing routine health screenings, especially in areas with high prevalence of HIV.

2. Procedure

The procedure for testing antibodies to HIV-1 and HIV-2 using CPT® Code 86703 involves several key steps:

  • Sample Collection A blood sample is collected from the patient, typically via venipuncture. This sample is essential for the subsequent testing process.
  • Laboratory Processing The collected blood sample is sent to a laboratory where it undergoes processing. The laboratory will prepare the sample for analysis using a qualitative chemiluminescent immunoassay.
  • Testing for Antibodies The qualitative test is performed to detect the presence of antibodies specific to HIV-1 and HIV-2. The assay works by using specific reagents that react with the antibodies if they are present in the sample.
  • Result Interpretation After the testing is complete, the laboratory interprets the results. A positive result indicates the presence of antibodies to either or both HIV-1 and HIV-2, while a negative result indicates their absence.
  • Reporting The results are compiled and reported back to the healthcare provider, who will discuss the findings with the patient and determine any necessary follow-up actions.

3. Post-Procedure

After the antibody testing for HIV-1 and HIV-2 is completed, the following post-procedure considerations are important:

Patients should be informed about the significance of their test results. If the test is positive, further confirmatory testing is typically required to establish a definitive diagnosis. Healthcare providers may also discuss the implications of a positive result, including treatment options and the importance of notifying sexual partners. In the case of a negative result, patients may still be advised on preventive measures, especially if they are at ongoing risk for HIV infection. Additionally, routine follow-up testing may be recommended based on individual risk factors and healthcare provider guidelines.

Short Descr HIV-1/HIV-2 1 RESULT ANTBDY
Medium Descr ANTIBODY HIV-1&HIV-2 SINGLE RESULT
Long Descr Antibody; HIV-1 and HIV-2, single result
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GA Waiver of liability statement issued as required by payer policy, individual case
92 Alternative laboratory platform testing: when laboratory testing is being performed using a kit or transportable instrument that wholly or in part consists of a single use, disposable analytical chamber, the service may be identified by adding modifier 92 to the usual laboratory procedure code (hiv testing 86701-86703, and 87389). the test does not require permanent dedicated space, hence by its design may be hand carried or transported to the vicinity of the patient for immediate testing at that site, although location of the testing is not in itself determinative of the use of this modifier.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
GZ Item or service expected to be denied as not reasonable and necessary
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q4 Service for ordering/referring physician qualifies as a service exemption
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
QW Clia waived test
U6 Medicaid level of care 6, as defined by each state
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2013-01-01 Changed Short Descriptor changed.
2012-01-01 Changed Description Changed
2011-01-01 Changed Short description changed.
1993-01-01 Added First appearance in code book in 1993.
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