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Official Description

Cyclic citrullinated peptide (CCP), antibody

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86200 refers to the laboratory test for measuring cyclic citrullinated peptide (CCP) antibody levels in the blood. This test is significant as it serves as a serum marker for rheumatoid arthritis, which is a chronic inflammatory condition primarily affecting the synovial membrane of joints. The presence of CCP antibodies can be an early indicator of rheumatoid arthritis, often detectable before the onset of clinical symptoms associated with the disease. The test is typically ordered alongside the rheumatoid factor test, identified by CPT® Code 86431, to provide a more comprehensive assessment of the patient's condition. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The serum obtained from the blood sample is then analyzed using a semiquantitative enzyme-linked immunosorbent assay (ELISA), a method that allows for the measurement of the concentration of CCP antibodies in the serum.

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