CPT® Code 86367

The CPT® Code 86367 refers to a laboratory test that quantifies the total count of CD34 stem cells. CD34 is a specific cell surface glycoprotein that plays a crucial role in the attachment of stem cells to the extracellular matrix of bone marrow or directly to stromal cells, which are supportive cells found in various tissues. This molecule is also essential for the migration of T cells into lymph nodes, highlighting its importance in the immune response. The measurement of CD34 stem cells is particularly significant for patients who are preparing for either autologous (using the patient's own stem cells) or allogenic (using stem cells from a donor) stem cell transplants. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The analysis of the whole blood sample is conducted using advanced techniques such as multi-colored immunofluorescence and flow cytometry, which allow for precise quantification and purification of hematopoietic progenitor stem cells. This detailed assessment is vital for determining the appropriate treatment plan and ensuring the best possible outcomes for patients undergoing stem cell transplantation.