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The Hemagglutination Inhibition (HAI) test, designated by CPT® Code 86280, is a laboratory procedure utilized for the identification of specific viruses or bacteria. This test is characterized by its simplicity, rapid execution, and high accuracy in detecting the presence of antigens or quantifying antibodies. The underlying principle of the HAI test involves the interaction between surface proteins of certain viruses and bacteria with red blood cells, leading to a phenomenon known as agglutination, where these pathogens clump together with the red blood cells to form a lattice-like structure. In the HAI test, a known quantity of antibodies is mixed with the antigen of interest and a fixed amount of red blood cells that are coated with the corresponding antigen. If the sample being tested contains the specific antigen, it will compete with the antigen coated on the red blood cells for binding to the introduced antibodies. This competition inhibits the agglutination process, allowing for the identification or quantification of the antigen or antibody present in the sample. The HAI test is a valuable tool in clinical diagnostics, providing essential information for the detection of infectious agents.
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The Hemagglutination Inhibition (HAI) test is performed for various clinical indications, particularly in the context of infectious diseases. The following conditions may warrant the use of this test:
The Hemagglutination Inhibition (HAI) test involves several key procedural steps that ensure accurate results. The following outlines the procedure:
Following the Hemagglutination Inhibition (HAI) test, the results are analyzed to determine the presence or absence of the specific antigen or to quantify the antibodies. Depending on the findings, further clinical evaluation may be necessary. If the test indicates a positive result for a viral or bacterial infection, appropriate treatment options can be discussed with the patient. Additionally, it is important to document the results accurately for future reference and to inform any necessary follow-up testing or interventions. The patient may be advised on any further steps based on the test outcomes, including potential treatments or additional diagnostic procedures.
| Short Descr | HEMAGGLUTINATION INHIBITION | Medium Descr | HEMAGGLUTINATION INHIBITION TEST HAI | Long Descr | Hemagglutination inhibition test (HAI) | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 235 - Other Laboratory |
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