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The CPT® Code 87472 refers to a laboratory test designed for the detection of the infectious agents Bartonella henselae and Bartonella quintana through the analysis of nucleic acids, specifically DNA or RNA. Bartonella is classified as a small, gram-negative bacillus that poses challenges in terms of isolation and culture in traditional laboratory settings. The use of nucleic acid probes facilitates the rapid identification of these specific Bartonella species by targeting their genetic material without the necessity for culturing the organisms. Bartonella henselae is primarily known for causing cat scratch disease (CSD), which can result in severe disseminated infections, while Bartonella quintana is linked to trench fever and bacillary angiomatosis, particularly in patients with HIV. The procedure employs advanced techniques such as polymerase chain reaction (PCR) or reverse transcriptase polymerase chain reaction (RT-PCR) to amplify the target sequences of Bartonella DNA or RNA, significantly enhancing the assay's sensitivity. This amplification process generates millions of copies of the target nucleic acid, which are then detected using DNA probes that are labeled with either fluorescent or chemiluminescent markers, ensuring specificity to the target sequence. Furthermore, the quantification aspect of this test allows for an assessment of the microbial load present in the sample, often utilizing quantitative or real-time PCR methods to provide detailed reports on the absolute or relative amounts of the detected nucleic acid sequences.
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The CPT® Code 87472 is indicated for the detection of specific infectious agents, particularly in the context of the following conditions:
The procedure for CPT® Code 87472 involves several critical steps to ensure accurate detection and quantification of the target nucleic acids. The process begins with the collection of a specimen, which may include blood or tissue samples from the patient suspected of having an infection caused by Bartonella species. Once the sample is obtained, it undergoes a nucleic acid extraction process to isolate the DNA or RNA present in the specimen. This step is crucial as it prepares the genetic material for amplification.
Post-procedure care for patients undergoing testing with CPT® Code 87472 typically involves monitoring for any potential side effects related to the specimen collection, such as minor discomfort or bruising at the site of blood draw. The results of the test are usually communicated to the healthcare provider, who will interpret the findings in the context of the patient's clinical presentation. Depending on the quantification results, further diagnostic or therapeutic measures may be considered to address the identified infection. It is essential for healthcare providers to ensure that patients understand the implications of the test results and any necessary follow-up actions.
| Short Descr | BARTONELLA DNA QUANT | Medium Descr | IADNA BARTONELLA HENSELAE&QUINTANA QUANTJ | Long Descr | Infectious agent detection by nucleic acid (DNA or RNA); Bartonella henselae and Bartonella quintana, quantification | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 206 - Microscopic examination (bacterial smear, culture, toxicology) |
| 59 | Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25. | 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. |
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| 2011-01-01 | Changed | Short description changed. |
| 1998-01-01 | Added | First appearance in code book in 1998. |
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