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Official Description

Infectious agent detection by nucleic acid (DNA or RNA); respiratory virus (eg, adenovirus, influenza virus, coronavirus, metapneumovirus, parainfluenza virus, respiratory syncytial virus, rhinovirus), includes multiplex reverse transcription, when performed, and multiplex amplified probe technique, multiple types or subtypes, 6-11 targets

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 87632 refers to a diagnostic test that detects infectious agents through the analysis of nucleic acids, specifically DNA or RNA, in respiratory specimens. This test is crucial for identifying various respiratory viruses, which may include adenovirus, influenza virus, coronavirus, metapneumovirus, parainfluenza virus, respiratory syncytial virus (RSV), and rhinovirus. The procedure involves collecting a respiratory specimen, which can be obtained through methods such as bronchoalveolar lavage, nasal wash, nasopharyngeal swab, or pleural fluid aspiration. Once the specimen is collected, it undergoes a sophisticated testing process that utilizes multiplex reverse transcription polymerase chain reaction (RT-PCR). This technique allows for the simultaneous extraction and amplification of nucleic acids from multiple types or subtypes of respiratory viruses. The amplified DNA or RNA fragments are then sized and analyzed to determine the specific viral types or subtypes present in the specimen. It is important to note that this code is specifically used when the test targets between 6 to 11 different types or subtypes of respiratory viruses. For tests targeting fewer types, such as 3-5, CPT® Code 87631 should be used, while CPT® Code 87633 is applicable for tests that target 12-25 types.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The CPT® Code 87632 is indicated for use in the detection of specific respiratory viral infections. The following conditions or symptoms may warrant the performance of this test:

  • Respiratory Symptoms Patients presenting with symptoms such as cough, fever, shortness of breath, or wheezing may require testing to identify the underlying viral cause.
  • Severe Respiratory Illness In cases of severe respiratory illness, particularly in immunocompromised patients or those with underlying health conditions, this test can help determine the specific viral agent responsible for the infection.
  • Outbreak Investigation During outbreaks of respiratory illnesses, this test can be utilized to quickly identify the viral pathogens involved, aiding in public health responses.
  • Diagnostic Confirmation The test may be used to confirm a diagnosis of a suspected viral respiratory infection when clinical presentation and other diagnostic methods are inconclusive.

2. Procedure

The procedure for CPT® Code 87632 involves several key steps to ensure accurate detection of respiratory viruses. The following outlines the procedural steps:

  • Specimen Collection A respiratory specimen is collected from the patient using one of several methods, including bronchoalveolar lavage, nasal wash, nasopharyngeal swab, or pleural fluid aspiration. The choice of method depends on the clinical scenario and the patient's condition.
  • Nucleic Acid Extraction Once the specimen is obtained, nucleic acids (DNA or RNA) are extracted from the respiratory specimen. This step is critical as it prepares the sample for amplification and analysis.
  • Multiplex Reverse Transcription The extracted nucleic acids undergo multiplex reverse transcription, which converts RNA into complementary DNA (cDNA) if RNA viruses are present. This process allows for the simultaneous analysis of multiple viral targets.
  • Amplification and Detection The cDNA is then amplified using a multiplex amplified probe technique. This step increases the quantity of the target nucleic acids, making them easier to detect. The amplification process is designed to target 6-11 specific types or subtypes of respiratory viruses.
  • Analysis After amplification, the resulting DNA or RNA fragments are sized and analyzed to identify the specific types or subtypes of respiratory viruses present in the specimen. This analysis provides the necessary information for diagnosis and treatment.

3. Post-Procedure

After the procedure associated with CPT® Code 87632, the following post-procedure considerations should be noted: The results of the test are typically available within a specified timeframe, depending on the laboratory's processing capabilities. Clinicians should review the results in conjunction with the patient's clinical presentation to make informed decisions regarding treatment and management. Additionally, it is essential to monitor the patient for any changes in their condition following the test, especially if a viral infection is confirmed. Proper documentation of the procedure and results is crucial for compliance and billing purposes.

Short Descr RESP VIRUS 6-11 TARGETS
Medium Descr IADNA RESPIRATRY PROBE & REV TRNSCR 6-11 TARGETS
Long Descr Infectious agent detection by nucleic acid (DNA or RNA); respiratory virus (eg, adenovirus, influenza virus, coronavirus, metapneumovirus, parainfluenza virus, respiratory syncytial virus, rhinovirus), includes multiplex reverse transcription, when performed, and multiplex amplified probe technique, multiple types or subtypes, 6-11 targets
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 206 - Microscopic examination (bacterial smear, culture, toxicology)
CR Catastrophe/disaster related
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2015-01-01 Changed Description Changed
2013-01-01 Added Added
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