CPT® Code 87480

The CPT® Code 87480 refers to the detection of infectious agents, specifically Candida species, through nucleic acid techniques, which can involve either DNA or RNA. This procedure utilizes a direct probe technique to identify the presence of Candida, a type of fungus that is typically found on the skin and in mucous membranes, including the vagina, mouth, and rectum. Under normal circumstances, Candida exists harmlessly; however, it can become pathogenic, leading to an infection known as Candidiasis moniliasis when there is a disruption in the body's chemical balance, allowing the fungus to proliferate uncontrollably. Certain populations, such as individuals on antibiotics, those who are immunocompromised, and infants, are particularly vulnerable to these infections. Candidiasis can manifest in various areas, including the mouth, skin, nails, and vagina, and in rarer cases, it may affect the esophagus or gastrointestinal tract. The nucleic acid tests for Candida are primarily conducted for vaginal infections and can include rapid testing methods that may be performed in a physician's office using specialized test kits. The process for CPT® Code 87480 involves obtaining a vaginal swab, which is then treated with a lysate to break down cells and release nucleic acids. This sample undergoes a series of steps, including incubation and washing, to detect the presence of Candida-specific nucleic acids, ultimately resulting in a color change that indicates a positive or negative result for the infection.