© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 87503 pertains to the detection of infectious agents through nucleic acid testing, specifically targeting the influenza virus. This test is designed to identify multiple types or subtypes of the influenza virus present in a laboratory specimen. Influenza viruses are categorized primarily into two main types: type A and type B. Within these categories, there are various subtypes, such as H1N1, H3N2, and H5N1, which can significantly impact public health. The process of nucleic acid detection involves extracting DNA or RNA from the specimen, which may include blood or other biological materials. The test utilizes advanced techniques such as multiplex reverse transcription, when applicable, and multiplex amplified probe techniques to enhance the accuracy and efficiency of the detection process. By employing reverse transcription polymerase chain reaction (RT-PCR), the test amplifies the extracted nucleic acids, allowing for precise identification of specific strains of the influenza virus. This coding is essential for accurate billing and documentation, as it distinguishes between different testing scenarios: CPT® Code 87501 is used for testing a single type or subtype, CPT® Code 87502 is designated for multiplex testing of the first two types or subtypes, and CPT® Code 87503 is specifically for each additional influenza type or subtype beyond the initial two tested.
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