CPT® Code 87633

Infectious agent detection by nucleic acid (DNA or RNA); respiratory virus (eg, adenovirus, influenza virus, coronavirus, metapneumovirus, parainfluenza virus, respiratory syncytial virus, rhinovirus), includes multiplex reverse transcription, when performed, and multiplex amplified probe technique, multiple types or subtypes, 12-25 targets

The CPT® Code 87633 refers to a diagnostic test that detects infectious agents through the analysis of nucleic acids, specifically DNA or RNA, in respiratory specimens. This test is designed to identify a range of respiratory viruses, which may include adenovirus, influenza virus, coronavirus, metapneumovirus, parainfluenza virus, respiratory syncytial virus (RSV), and rhinovirus. The procedure involves collecting a respiratory specimen, which can be obtained through various methods such as bronchoalveolar lavage, nasal wash, nasopharyngeal swab, or pleural fluid aspiration. Once the specimen is collected, it undergoes a sophisticated testing process that utilizes multiplex reverse transcription polymerase chain reaction (RT-PCR). This technique allows for the simultaneous extraction and amplification of DNA or RNA from multiple types or subtypes of respiratory viruses. The amplified nucleic acid fragments are then sized and analyzed to determine the specific viral types or subtypes present in the specimen. This code is specifically applicable when testing for 12 to 25 different targets, providing a comprehensive assessment of potential viral infections in the respiratory tract. For tests involving fewer targets, different codes are utilized: CPT® Code 87631 is used for 3-5 targets, and CPT® Code 87632 is designated for 6-11 targets.