CPT® Code 87635

Infectious agent detection by nucleic acid (DNA or RNA); severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]), amplified probe technique

The CPT® Code 87635 refers to the detection of infectious agents through nucleic acid amplification techniques, specifically targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease (COVID-19). This procedure utilizes an amplified probe technique to identify the presence of the virus's genetic material, either DNA or RNA, in a sample. Nucleic acid amplification tests (NAATs) are highly sensitive and capable of detecting even minute quantities of viral genetic material, making them essential for accurate diagnosis. The process involves amplifying a specific segment of the viral RNA, which is first converted into DNA through a reverse transcription process, allowing for effective detection. Samples for testing can be collected from various respiratory sites, including the nose, throat, bronchus, or lungs, using methods such as swabbing or bronchoalveolar lavage. The procedure is critical in confirming the presence of SARS-CoV-2, especially in symptomatic individuals or during outbreaks, and plays a vital role in public health efforts to control the spread of COVID-19.