CPT® Code 87631

Infectious agent detection by nucleic acid (DNA or RNA); respiratory virus (eg, adenovirus, influenza virus, coronavirus, metapneumovirus, parainfluenza virus, respiratory syncytial virus, rhinovirus), includes multiplex reverse transcription, when performed, and multiplex amplified probe technique, multiple types or subtypes, 3-5 targets

The CPT® Code 87631 refers to a diagnostic test that detects infectious agents through the analysis of nucleic acids, specifically DNA or RNA, in respiratory specimens. This test is crucial for identifying various respiratory viruses, which may include adenovirus, influenza virus, coronavirus, metapneumovirus, parainfluenza virus, respiratory syncytial virus (RSV), and rhinovirus. The procedure involves obtaining a respiratory specimen through methods such as bronchoalveolar lavage, nasal wash, nasopharyngeal swab, or pleural fluid aspiration. Once the specimen is collected, it undergoes a sophisticated testing process that utilizes multiplex reverse transcription polymerase chain reaction (RT-PCR). This technique allows for the extraction and amplification of DNA or RNA from multiple types or subtypes of the targeted respiratory viruses. The amplified nucleic acid fragments are then sized and analyzed to determine the specific types or subtypes present in the specimen. This code is specifically designated for tests that target 3 to 5 different types or subtypes of respiratory viruses, providing healthcare professionals with essential information for diagnosis and treatment planning.