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Official Description

Androstanediol glucuronide

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82154 refers to a laboratory test that measures the levels of androstanediol glucuronide in the blood. Androstanediol glucuronide is a metabolite of androgens, which are hormones that play a crucial role in various bodily functions. This specific hormone is produced primarily by the liver, prostate, and skin, and serves as an important marker for assessing peripheral androgen metabolism and its biological effects. The measurement of androstanediol glucuronide levels is particularly significant in the evaluation of conditions such as idiopathic hirsutism in women, where abnormal levels may indicate an underlying hormonal imbalance. The test involves obtaining a blood sample through a procedure known as venipuncture, which is separately reportable. Following the collection of the blood sample, the testing is conducted using a quantitative radioimmunoassay (RIA) technique, which includes the hydrolysis of glucuronide and subsequent chromatography to accurately quantify the levels of the hormone in the sample.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The measurement of androstanediol glucuronide levels is indicated for the evaluation of hormonal conditions, particularly in women presenting with symptoms of androgen excess. The following conditions may warrant this test:

  • Idiopathic Hirsutism Abnormal levels of androstanediol glucuronide may be found in women with this condition, which is characterized by excessive hair growth in areas where men typically grow hair.

2. Procedure

The procedure for measuring androstanediol glucuronide levels involves several key steps that ensure accurate results. First, a blood sample is obtained from the patient through a process known as venipuncture. This procedure involves inserting a needle into a vein, typically in the arm, to draw a sufficient volume of blood for testing. It is important that this step is performed by a qualified healthcare professional to minimize discomfort and ensure the integrity of the sample. Once the blood sample is collected, it is processed for testing. The sample undergoes hydrolysis of glucuronide, which is a chemical reaction that breaks down the glucuronide compound to release androstanediol. Following hydrolysis, chromatography is performed, a technique that separates the components of the sample based on their chemical properties. Finally, the levels of androstanediol glucuronide are quantified using a quantitative radioimmunoassay (RIA), a sensitive method that allows for precise measurement of hormone levels in the blood.

3. Post-Procedure

After the blood sample has been collected and processed, there are generally no specific post-procedure care requirements for the patient. However, it is advisable for patients to remain hydrated and to follow any additional instructions provided by the healthcare professional. The results of the androstanediol glucuronide test will typically be reviewed by the physician, who will interpret the findings in the context of the patient's clinical presentation and may recommend further evaluation or treatment based on the results.

Short Descr ANDROSTANEDIOL GLUCURONIDE
Medium Descr ANDROSTANEDIOL GLUCURONIDE
Long Descr Androstanediol glucuronide
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
1994-01-01 Added First appearance in code book in 1994.
Code
Description
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