CPT® Code 84285

The CPT® Code 84285 refers to a laboratory test specifically designed to measure the levels of silica in the blood or urine. Silica, a mineral commonly found in the environment, is typically present in the body in a bound form, associated with proteins and lipids. It plays a crucial role in the structure of collagen, which is essential for maintaining the elasticity of the skin and the strength of bones. Elevated levels of silica can indicate various health issues, particularly those related to occupational exposure to inhaled silica particles. Such exposure is often linked to conditions like silicosis, lung cancer, pulmonary tuberculosis, chronic airway diseases, autoimmune disorders, and chronic renal failure. The testing process involves obtaining a blood sample through a procedure known as venipuncture, which is separately reportable. For urine testing, a sample is collected from a random void. The analysis of serum or plasma is conducted using quantitative inductively coupled plasma/atomic emission spectrometry, while urine samples are analyzed using quantitative inductively coupled plasma/optical emission spectrometry. It is important to note that the use of gadolinium contrast media within 48 hours prior to urine sample collection may interfere with the test results, potentially leading to inaccurate measurements of silica levels.