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Official Description

Vasopressin (antidiuretic hormone, ADH)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84588 refers to a laboratory test that measures the levels of arginine vasopressin, also known as antidiuretic hormone (ADH), in the blood. This hormone plays a crucial role in the regulation of water balance, glucose, and sodium levels within the bloodstream. Synthesized in the hypothalamus, ADH is stored in the posterior pituitary gland until it is released into the bloodstream in response to specific physiological conditions, particularly dehydration. When the body experiences a lack of water, ADH is secreted to prompt the kidneys to conserve water, thereby concentrating urine and reducing urine volume. Additionally, ADH contributes to the regulation of blood pressure by increasing peripheral vascular resistance through vasoconstriction, which can lead to elevated blood pressure levels. The test involves obtaining a blood sample through a procedure known as venipuncture, which is separately reportable. The plasma obtained from the blood sample is then analyzed using a quantitative radioimmunoassay method to determine the concentration of vasopressin present.

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